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Alkol kullanmayan bir hastada "İZOLE" GGT yüksekliğinin nedeni ne olabilir?
Aklıma takılan bir gastroenteroloji sorusudur bu.
Unutmadan, hasta diabetik de değil.
- hlathguth
(16.05.08 16:35:30)
www.gp-training.net
2. Isolated rise in GGT
...is caused by:
a) Alcohol abuse. This is a common cause. If history is corroborative, nothing need be done, except for advice on abstinence.
b) Fatty Liver or non-alcoholic steatohepatosis (NASH). This is especially common in middle-aged overweight women. Causes include diabetes mellitus hyperlipidemia and obesity. They will need testing for fasting lipids, fasting glucose and an Ultrasound abdomen. The latter may corroborate the diagnosis. Appropriate treatment is instituted for diabetes and hyperlipidemia. Referral to dietician is needed. Hospital referral is indicated only if GGT is above 150.
c) Drugs acting as enzyme-inducers also frequently raise GGT in isolation. They include Pheytoin, Carbamazepine and Barbiturates etc. If patient is on other drugs, a check through BNF is advised or contact your pharmacist.
2. Isolated rise in GGT
...is caused by:
a) Alcohol abuse. This is a common cause. If history is corroborative, nothing need be done, except for advice on abstinence.
b) Fatty Liver or non-alcoholic steatohepatosis (NASH). This is especially common in middle-aged overweight women. Causes include diabetes mellitus hyperlipidemia and obesity. They will need testing for fasting lipids, fasting glucose and an Ultrasound abdomen. The latter may corroborate the diagnosis. Appropriate treatment is instituted for diabetes and hyperlipidemia. Referral to dietician is needed. Hospital referral is indicated only if GGT is above 150.
c) Drugs acting as enzyme-inducers also frequently raise GGT in isolation. They include Pheytoin, Carbamazepine and Barbiturates etc. If patient is on other drugs, a check through BNF is advised or contact your pharmacist.
- ermanen (16.05.08 18:35:11 ~ 18:35:53)
çok teşekkürler!
- hlathguth (29.06.08 17:29:31)
1
